BRESCIANI ROBERTO

IProf. Roberto Bresciani was born on August 26, 1962 in Brescia.
April 1986: M.S. degree in Biological Sciences at the University of Milano.
December 1986: Fellowship at the Department for "Basic Biomedical Sciences" of the University of Brescia from the "Consorzio Ente Universitario Lombardia Orientale" (E.U.L.O.).
November 1989: Fellowship for "Research at foreign Universities" from the Italian University Ministry.
From October 1990 to July 1992: Visiting Fellow at the Zentrum fur Biochemie und Molekulare Zellbiologie, Georg-August Universitat Goettingen (Germany), directed by Prof. Kurt von Figura.
March 1990: Fellowship for "Research at foreign Universities" from the Italian Society of Biochemistry.
October 1992: Fellowship for "Study and research at foreign Universities" from the Permanent Conference of the Italian Universities Rectors (C.R.U.I.).
October 1992 to February 1993: Visiting Fellow at the Zentrum fur Biochemie und Molekulare Zellbiologie, Georg-August Universitat Goettingen (Germany).
February 1993: University Researcher at the Department of "Biomedical Sciences and Biotechnology" at the University of Brescia.
October 1993: Ph.D. degree in "Cellular and Molecular Biotechnology Applied to Biomedical Sciences" of the University of Brescia. Thesis title: "Lysosomal enzymes and their receptors: intracellular transport, loss of the recognition signal and receptor sorting in polarized cells".
October 1996: Specializing degree in "Biochemistry and Clinical Chemistry" at the Medical Faculty of the University of Brescia.
From 2000/01 up to 2012/13: member of the Ph.D. Program in "Cellular and Molecular Biotechnology Applied to Biomedical Sciences" of the University of Brescia.
From 2002: Associated Professor of Biochemistry at the Medical Faculty of the University of Brescia.
From 2002 to 2004: member of the Scientific and Organizing Committee for the Biotechnology School at the University of Brescia for different projects funded by the European Social Funding (F.S.E.), the Lombardy Region and the University of Brescia.
November 2005: confirmed as Associated Professor of Biochemistry at the Medical Faculty of the University of Brescia.
From November 2012 up to today: member of the Department of Molecular and Translational Medicine at the University of Brescia.
From 2012 up to today: Delegate of the Head of the Department of Molecular and Translational Medicine at the University of Brescia for incoming students, tutoring and third mission.
From 2013: member of the Ph.D. Program in "Molecular genetics, Biotechnology and Experimental medicine" of the University of Brescia.
From 2014 to 2016: Delegate of the Chancellor of University of Brescia for incoming students and tutoring.
From 2014 up to today: Delegate for the University of Brescia, Program of Science, for "I Lincei per una nuova didattica nella scuola" in collaboration with the Accademia dei Lincei in Rome
He was designated as member in different commissions for the final Ph.D. degree in different Italian Universities.
He was designated as member in different commissions for the enrolment of University Researchers in different Italian Universities.
He has participated as member of Research Unit at different Research Programs (PRIN, FIRB, CARIPLO).
Teacher of Biochemistry in the Medical and Surgery, the Dentistry and the Biotechnology Courses at the University of Brescia.
Teacher of Biochemistry in different medical Specializing Schools at the University of Brescia.
Head of the Committee of the medical Specializing School in Clinical Pathology and clinical Biochemistry at the University of Brescia.




During his scientific career Prof. Roberto Bresciani dedicated himself to the following topics:
study of the biochemical and molecular aspects that regulate the maturation and intracellular transport of lysosomal enzymes and their associated receptors;
study of the metabolism of sialoglycoconjugates, with a particular interest to gangliosides;
cloning and biochemical characterization of different forms of sialidases, enzymes that are involved in the removal of sialic acid residues from the oligosaccharide antennas of different sialoglycoconjugates;
study of the post-translational processing of the sialidase form known to be associated to cellular membranes;
study of the localization of the membrane associated sialidase in the different subcompartments of the plasma membrane;
study the role of the different sialidases in the regulation of cellular and molecular mechanisms in different tumors;
biochemical characterization of the sialic acid acetyl-esterase;
cloning of sialidases, sialic acid acetyl-esterase and other different proteins in zebrafish (Danio rerio) and biochemical and functional study of the role of these proteins during the development of zebrafish;
biochemical characterization of exosomal vesicles and analysis of these biological structures as carriers of different biological activities, including the membrane associated form of sialidase.