Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases.

Aged, Atropine; pharmacology, Benzofurans; pharmacology, Carbachol; pharmacology, Cell Proliferation, Cells; Cultured, Cholinergic Agonists; pharmacology, Gene Expression, Humans, Male, Mitogen-Activated Protein Kinases; metabolism, Muscarinic Antagonists; pharmacology, Myocytes; Smooth Muscle; metabolism, Phosphatidylinositol 3-Kinases; metabolism, Piperidines; pharmacology, Pirenzepine; analogs /&/ derivatives/pharmacology, Proto-Oncogene Proteins c-akt; metabolism, Pyrrolidines; pharmacology, RNA; Messenger; metabolism, Receptors; Muscarinic; physiology, Urinary Bladder; cytology