IL-21 is the primary common gamma chain-binding cytokine requiredfor human B-cell differentiation in vivo.

Recher, M; Berglund, Lj; Avery, Dt; Cowan, Mj; Gennery, Ar; Smart, J; Peake, J; Wong, M; Pai, Sy; Baxi, S; Walter, Je; Palendira, U; Tangye, Ga; Rice, M; Brothers, S; Al Herz, W; Oettgen, H; Eibel, H; Puck, Jm; Cattaneo, F; Ziegler, Jb; Giliani, Silvia Clara; Tangye, Sg; Notarangelo, L. D.