BLOOD

Rivista

Codice:

E023052

ISSN:

0006-4971

Dati Generali

Pubblicazioni (277)

3-YEARS and Beyond Study Completion Results of the Otpkima Randomized Clinical Trial in Elderly CML Patients

Abstract

A 17q25.3 duplication defines a new dosage-sensitive congenital neutropenia locus and implicates SOCS3 as a candidate gene for cases unexplained by ELA2 mutation.

Abstract

A Cellular Therapy with Haploidentical Peripheral Hematopoietic Stem Cell Transplantation MAY be a Therapeutic Option in Patients with Relapsed Lymphoma with Chemorefractory Disease

Articolo

A Gene Panel NGS-Based Strategy for Genomic Characterization of Acute Myeloid Leukemias (AMLs)

Abstract

A cell surface molecule selectively expressed on murine Natural Interferon Producing Cells that blocks secretion of interferon-alpha.

Articolo

A comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of patients with high risk, Ph-pos, chronic myeloid leukemia. An ELN Study.

Articolo

A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)

Articolo

A lymphomagenic role for HIV beyond immune suppression?

Articolo

A phase 3 randomized trial of mavorixafor, a CXCR4 antagonist, for WHIM syndrome

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A randomized study of alphaInterferon vs. alphaInterferon and low dose arabinosyl cytosine in chronic myeloid leukemia

Articolo

AIDA (All-trans-retinoic acid + Idarubicin) in newly diagnosed acute promyelocytic leukemia.

Articolo

AIDA: The italian way of treating acute promyelocytic leukemia (APL): final act .

Abstract

AML1-ETO trabscript expression patterns in acute myeloid leukemia patients with t(8;21) in complete haematological remission

Abstract

ANTI-CMV Immunoglobulins in Association with ANTI-CMV Drugs in Patients with Hematological Malignancies Submitted to Allogeneic STEM CELL Transplantation: A MULTI-Center Retrospective Experience

Abstract

Absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy in folliculin-interacting protein 1 deficiency

Articolo

Activation of phospholipase D by interleukin 8 in human neutrophils

Articolo

Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14

Articolo

Adherence to the mediterranean diet is associated with lower platelet and leucocyte counts: results from the Moli-sani study

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Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation.

Articolo

Adhesion, transendothelial migration, and reverse transmigration on in vitro cultured dendritic cells.

Articolo

Aggressive Aneuploid Acute Myeloid Leukemia Is Dependent on Alterations of P53, Gain of APC and PLK1 and Loss of RAD50

Abstract

Allogeneic transplantation improves the overall and progression-free survival of Hodgkin's lymphoma patients relapsing after autologous transplantation: a retrospective study based on the time of HLA typing and donor availability

Articolo

Alteration of BIRC3 and multiple other NF-{kappa}B pathway genes in splenic marginal zone lymphoma

Articolo

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Articolo

Altered leukocyte response to CXCL12 in patients with Warts Hypogammaglobulinemia, Infections, Myelokathexis (WHIM) syndrome

Articolo

Analysis of ferritins in lymphoblastoid cells lines and in the lens of subjects with hereditary hyperferritinemia-cataract syndrome.

Articolo

Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function

Articolo

Analysis of the biological functions of H-and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Articolo

Angiopoietin-1 mediates the pro-angiogenic activity of the bone morphogenic protein antagonist Drm

Articolo

Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.

Articolo

Anti-CD3{epsilon} mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications

Articolo

Antiangiogenic therapy with thalidomide improves anemia, thrombocytopenia, hyperleucocytosis, splenomegaly in idiopathic myelofibrosis.

Abstract

Antiproliferative Effects of Tyrosine Kinase (STI 571) and Farnesyl Transferase Inhibitors (R115777 and SCH66336) on Acute Leukemia Human Tumor Cell Lines.

Abstract

Assessment of BCR-ABL1 Transcript Levels By Digital PCR (dPCR) in CML Patients who Achieved a Deep Molecular Response (DMR: MR4.0, MR4.5 And MR5.0) with Tkis May Improve the Detection of Minimal Residual Disease (MRD) and the Selection of Patients for Treatment Free Remission (TFR)

Abstract

Assessment of Liver Damage with Transient Hepatic Elastography (FIBROSCAN) in patients with chronic Graft-Versus-Host Disease.

Abstract

Assessment of Transitioning from High-Potency to Low-Potency Inhibitors in Chronic Myeloid Leukemia (CML) Patients: The Downgrading-Impact Project, a CML Campus Study

Abstract

Autologous Stem Cell Transplantation before Lymphocyte Apheresis for CAR-T Cells Therapy Negatively Impacts on T-Cells Fitness and NK Cell Levels in DLBCL Patients

Abstract

Azacitidine Low-Dose Schedule In Low-Risk Myelodysplastic Syndromes. Preliminary Results of a Multicenter Phase II Study

Contributo in Atti di convegno

BDCA-2 (CD303): a highly specific marker for normal and neoplastic plasmacytoid dendritic cells.

Articolo

Betaherpesvirus Reactivation and Toll-Like Receptor Expression After Allogeneic Stem Cell Transplantation.

Abstract

Beyond presence: Clinical relevance of FLT3-ITD length and location in Acute Myeloid Leukemia (AML)

Abstract

Biologic and clinical significance of red cell ferritin

Articolo

Blockade of human P2X7 receptor function with a monoclonal antibody.

Articolo

Bone Marrow Tfr2 Deletion Modulates Systemic Metabolism in β-Thalassemic Mice to Sustain Augmented Erythropoiesis

Abstract

Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor.

Articolo

Bortezomib-thalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma.

Articolo

CCL16 activates an angiogenic program in vascular endothelial cells

Articolo

CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets.

Articolo

CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: A potential new link between adaptive and innate immunity

Articolo

Calcitonin receptor-like receptor guides arterial differentiation in zebrafish.

Articolo

Characteristics and expression of binding sites specific for ferritin H-chain an human cell lines

Articolo

Clinical and Biological EFFECTS of 5-Azacitidine FIVE Days/Monthly Schedule IN Symptomatic LOW-RISK (IPSS: 0-1) Myelodisplastic Patient.

Abstract

Co-inheritance of Gilbert syndrome increases the risk for developing gallstones in patients with hereditary spherocytosis.

Articolo

Comparative Somatic Mutational Profiling of CD34+ Hematopoietic Precursors (HSC) and Circulating Endothelial Cells (CEC) in Patients with Primary Myelofibrosis (PMF)

Abstract

Comparative Study on Fresenius-ATG Versus Thymoglobuline-ATG for the Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Stem Cell Transplantation from Matched Unrelated Donor: A Single Center Experience on 76 Patients

Abstract

Comparative monitoring of deep molecular response (DMR) by RT-quantitative (RT-qPCR) and digital PCR (dPCR) in Ph+ Chronic Myeloid Leukemia (CML) patients treated with TKIs for recognition of stable deep molecular response (DMR) and identification of best candidates to TKIs treatment discontinuation.

Abstract

Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: A European LeukemiaNet Study

Articolo

Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity

Articolo

Correlation between BCR::ABL1 Transcript LEVEL in Circulating Extracellular Vesicles and BOTH the Molecular Response and the Ongoing Therapy: A Study on Adult CML Patients

Abstract

Cytokine gene expression in B-cell chronic lymphocytic leukemia: evidence of constitutive interleukin-8 (IL-8) mRNA expression and secretion of biologically active IL-8 protein.

Articolo

Cytokine patterns and lymphocyte subsets in patients with chronic graft versus host disease after allogeneic stem cell transplantation with reduced intensity conditioning.

Abstract

DHPLC scan of iron genes in consecutive patients with suspected iron overload

Abstract

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

Articolo

Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients

Articolo

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis.

Articolo

Development of autologous, oligoclonal, poorly functioning T lymphocytes in a patient with autosomal recessive severe combined immunodeficiency caused by defects of the Jak3 tyrosine kinase.

Articolo

Different molecular behavior of CD40 mutants causing hyper-IgM syndrome.

Articolo

Digital PCR (dPCR) Overcomes the Limitations in Detection and in Quantification of Quantitative PCR (qPCR) and Reveals Different Levels of BCR-ABL1 Copies/µl Among the Chronic Myeloid Leukemia (CML) Patients Achieving Major (MR3.0) or DEEP (MR4.0, MR4.5 and MR5.0) Molecular Response with Tyrosin Kynase Inhibitors (TKIs)

Abstract

Divergent effects of hypoxia on dendritic cell functions.

Articolo

Divergent effects of interleukin-4 and interferon-γ on macrophage-derived chemokine production: an amplification circuit of polarized T helper 2 responses

Articolo

Do Unexpected and Cryptic FISH Lesions Of Chromosomally Normal MDS Patients Have Any Prognostic Relevance?

Abstract

Do chromosomal abnormalities show up during mesenchymal stromal cell expansion?

Articolo

Down regulation of TOPK, PBX3, SRPK, DDX21 and CLC genes in newly diagnosed early chronic phase chronic myeloid leukemia ptients treated with imatinib mesylate.

Abstract

Dramatic improvment in CR rate and CR duration with imatinib in adult and elderly Ph+ ALL patients: results of the GIMEMA prospective study LAL0201.

Abstract

Drug Resistance and Bcr-Abl Kinase Domain Mutations In Philadelphia-Positive Acute Lymphoblastic Leukemia From the Imatinib to the 2nd-Generation Tyrosine Kinase Inhibitor Era: The Main Changes Are In the Type of Mutations, but Not In the Frequency of Mutation Involvement.

Abstract

ELA2 genotype-phenotype correlation to be expected in patients with severe congenital neutropenia

Articolo

Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome

Articolo

Effect of acidic and basic isoferritins on in vitro growth of human granulocyte-monocyte progenitors

Articolo

Effects and outcome of a policy of intermittent imatinib treatment in elderly patients with chronic myeloid leukemia.

Articolo

Efficacy and toxicity of FLAI vs ICE for induction treatment of newly diagnosed AML paztients, younger than 60 years

Abstract

Efficacy and toxicity of FLAI-G-CSF and mylotarg for induction/consolidation of AML patients not treatable with conventional chemotherapy.

Abstract

Efficacy of Gemtuzumab Ozogamicin plus cytarabine in the treatment of poor risk acute myeloid leukemia.

Abstract

Efficacy of Glivec /STI571 in conjunction with alpha-interferon in a case of relapsed p190 BCR-ABL positive acute lymphoblastic leukemia.

Abstract

Engrafted maternal T cells in a severe combined immunodeficiency patient express T-cell receptor variable beta segments characterized by a restricted V-D-Jjunctional diversity

Articolo

Erratum: Effects and outcome of a policy of intermittent imatinib treatment in elderly patients with chronic myeloid leukemia (Blood (2013) 121:26 (5138-5144))

Articolo

Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival.

Articolo

Establishing a New Zebrafish Model to Study Malignant Transformation in Myeloproliferative Disorders.

Abstract

European multicenter experience on idiopathic hypereosynophilic syndrome with FIP1L1-PDGFR-alpha rearrangement treated with imatinib

Abstract

Evaluation of Circulating Endothelial Cells (CECs) As Marker of Endothelial Damage in Allo-Transplanted Patients at High Risk of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS): The Cecinvod Study

Abstract

Evidence for antigenic selection of large granular lymphocytes in a patient with Wiskott-Aldrich syndrome

Articolo

Exome sequencing reveals a pallidin mutation in a Hermansky-Pudlak-like primary immunodeficiency syndrome

Articolo

Expression of Toll-Like Receptors on Peripheral Blood Cells After Allogeneic Stem Cell Transplantation: Results of a Prospective Study.

Abstract

FIP1L1-PDGFRalpha Positive Hypereosinophilic Syndrome (HES). The Response to Imatinib (IM) Is Durable. A Report of 21 Patients with a Follow-Up of 12 to 67 Months.

Abstract

Ferritin is secreted via 2 distinct nonclassical vesicular pathways.

Articolo

First Interim Report of the Italian Multicentric Phase-III Randomized Study to Optimize TKIs Multiple Approaches - (OPTkIMA) in Elderly Patients (older than 60 years) with Ph+ Chronic Myeloid Leukemia (CML) and MR3.0/ MR4.0 Stable Molecular Response

Abstract

Fludarabine Based Regimen (FLAI) Is an Effective Treatment for Induction of Multidrug Resistant Pgp-Positive Acute Myeloid Leukemia Patients.

Abstract

Four Drugs Combination (Fludarabine, Cytarabine, Idarubicin, Etoposide) as Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia Patients Younger Than 65 Ys: Response and Follow-up of 84 Patients.

Abstract

Functional Characterization Of Natural Killer Cells In Type I Leukocyte Adhesion Deficiency

Articolo

Functional defects of dendritic cells in patients with CD40 deficiency.

Articolo

Fungal and bacterial infections in acute myeloid leukemia patients treated with induction regimens including fludarabine: a retrospective analysis of 224 cases.

Abstract

G-CSF treatment of Severe Congenital Neutropenia reverses neutropenia but does not correct the underlying functional deficiency of the neutrophil in defending against microorganisms.

Articolo

Gemtuzumab-Ozogamicin Containing Regimens As Induction Therapy Give the Highest Complete Remission Rate and the Longest Overall Survival Compared with Other Induction Regimens in Patients with Newly Diagnosed Acute Myeloid Leukemia

Abstract

Genetic and phenotypic attributes of splenic marginal zone lymphoma

Articolo

Genome wide DNA-profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome

Articolo

Genome-Wide Analysis by High-Resolution SNP Array Identifies Novel Genomic Alterations in Acute Promyelocytic Leukemia (APL).

Abstract

Genomic Analysis Of Notch Mutations In a Case Of Alagille Syndrome With Acute Lymphoblastic Leukemia

Abstract

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

Articolo

Gentuzumab Ozogamycin (Mylotarg) for the treatment of relapsed/refractory acute myeloid leukemia. A single Centre experience.

Abstract

Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo

Articolo

Gremlin is a novel agonist of the major pro-angiogenic receptor VEGFR2

Articolo

HIV-1 Tat and heparan sulfate proteoglycans: a novel mechanism of lymphocyte adhesion and migration across the endothelium

Articolo

HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activation

Articolo

Halting the FGF/FGFR axis leads to anti-tumor activity in Waldenström's Macroglobulinemia by silencing MYD88

Articolo

Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells.

Articolo

Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo.

Articolo

Hereditary hyperferritinemia-cataract syndrome: Relationship between phenotypes and specific mutations in the iron-responsive element of ferritin light-chain mRNA.

Articolo

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype

Articolo

High-dose therapy and autologous peripheral blood stem cell transplantation as salvage treatment for AIDS-related lymphoma: long-term results of the Italian Cooperative Group on AIDS and Tumors (GICAT) study with analysis of prognostic factors

Articolo

How I treat warts, hypogammaglobulinemia, infections, and myelokathexis syndrome

Articolo

Human CD34 + cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature

Articolo

Human CD34+ Cells Expressing Membrane-Bound Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Exert a Potent Anti-Lymphoma Effects by Targeting Tumor Vasculature

Abstract

Human blood IgM "memory" B cells are circulanting splenic marginal zone B cells harboring a trediversified immunoglobulin repertoire.

Articolo

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

Articolo

Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

Articolo

Human herpesvirus 8 acute infection of endothelial cells induces monocyte chemoattractant protein-1-dependent capillary-like structure formation: role of IKK/NF-(kappa)B pathway

Articolo

Human herpesvirus 8 enhances human immunodeficiency virus replication in acutely infected cells and induces reactivation in latently infected cells.

Articolo

Human immunodeficiency virus replication induces monocyte chemotactic protein-1 in human macrophages and U937 promonocytic cells.

Articolo

Human neutrophils interact with both 6-sulfo LacNAc+ DC and NK cells to amplify NK-derived IFN{gamma}: role of CD18, ICAM-1 and ICAM-3

Articolo

Hyperactive Erythropoiesis Induced By Hematopoietic Tfr2 Deletion Corrects Glucose Abnormalities in β-Thalassemic Mice

Abstract

Hypomorphic Rag mutations can cause destructive midline granulomatous disease

Articolo

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development

Articolo

IL-12 is chemiotactic for NK cells and stimulates their interaction with vascular endothelium.

Articolo

IL-21 is the primary common gamma chain-binding cytokine requiredfor human B-cell differentiation in vivo.

Articolo

Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP)

Articolo

Identification of Philadelphia-negative granulocyte-macrophage colony-forming units generated by stroma-adherent cells from chronic myelogenous leukemia patients.

Articolo

Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells

Articolo

Identification of a Novel Mutation Predisposing to Familial AML and MDS Syndrome By a NGS Approach

Abstract

Idiopathic hypereosinphilic synndrome (HES) with FIP1L1-PDGFR-alpha rearrangement can be effectively treated with imatinib

Abstract

Imatinib Mesylate Can Induce Molecular Complete Remission in Idiopathic Hypereosinophilic Syndrome (HES). A Phase II Multicentric Italian Clinical

Abstract

Imatinib Mesylate can induce complete molecular remission in FIP1L1-PDGFR-alpha positive idiopatic hypereosinophilic sindrome.

Abstract

Imatinib and pegylated human recombinant interferon-a2b in early chronic phase chronic myeloid leukemia.

Articolo

Imatinib mesylate in the treatment of c-kit-positive acute myeloid leukemia: is this the real target?

Articolo

Imatinib seems to be inefective in patients with systemic mastocytosis carrying the Asp816Val c-kit mutation.

Abstract

Immune Defects of B- and T-Cell Compartments in Natalizumab-Induced Progressive Multifocal Leukoencephalopathy

Abstract

Immune Reconstitution after Allogenic Stem Cell Transplantation in Patients with Myelofibrosis

Abstract

Immunologic differences in human isoferritins: implication for quantitation of serum ferritin

Articolo

Impaired NK cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced {beta}2 integrin high-affinity state

Articolo

Impaired natural and CD16-mediated NK cell cytotoxic function in WAS and XLT patients: ability of IL-2 to correct NK cell functional defect

Articolo

Impairment of dendritic cell functions in patients with adaptor protein-3 complex deficiency

Articolo

Incidence and Outcome of Bacterial Blood Stream Infections in Allotransplanted Patients: Rethinking the Role of Fluoroquinolone Prophylaxis

Abstract

Incidence of Thrombo-Embolic Events in Relation to Activated Prothrombin Complex Concentrate Exposure: A Literature Meta-Analysis

Abstract

Index of Bone Marrow Output and Imbalance of B-Lymphocyte Homeostasis before and after Transplantation Correlate Differently with Graft-Versus-Host Disease and Relapse

Abstract

Induction Intensified Regimens Including Fludarabine or Mylotarg for Acute Myeloid Leukemia Patients: Comparison by Response and Follow-up.

Abstract

Inhibition of vascular endothelial growth factor receptor 2 - mediated endothelial cell activation by Axl tyrosine kinase receptor.

Articolo

Innate immunity defects in Hermansky-Pudlak type 2 syndrome

Articolo

Interferon gamma in chronic myeloid leukemia: dose and side effects.

Articolo

Interleukin-15 (IL-15) induces IL-8 and monocyte chemotactic protein 1 production in human monocytes.

Articolo

Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line.

Articolo

Intermittent Imatinib (INTERIM) Treatment of Patients with Ph+ Chronic Myeloid Leukemia in Complete Cytogenetic Response: Cytogenetic and Molecular Data At One Year.

Abstract

Intrathymic restriction and peripheral expansion of the T cell repertoire in Omenn syndrome

Articolo

Invasive Pulmonary Aspergillosis in Acute Leukemia in the Era of New Antifungal Treatment and Prophylaxis Is Still Frequent, Even in Patients with Acute Lymphoblastic Leukemia, and Adversely Affects the Overall Treatment Outcome. Results of a 5-Year Study at a Single Institution

Abstract

Italian Cooperative study on idiopathic hypereosinophilic syndrome (HES): FIP1-L1/PDGFRA rearrangement can be effectively treated with Imatinib.

Abstract

Lack of iNKT cells in patients with combined immune deficiency due to hypomorphic RAG mutations.

Articolo

Leukemia inhibitory factor induces IL-8 and MCAF in human monocytes: differential regulation by IFN-gamma

Articolo

Long Term Follow-up of Ph+ CML Patients Achieving Complete Cytogenetic Response (CCgR) with Interferon Based Therapy - GIMEMA Protocol CML0509.

Abstract

Long-Term Mutation Follow-up of Philadelphia-Chromosome Positive Leukemia Patients Treated with Second-Generation Tyrosine Kinase Inhibitors after Imatinib Failure Shows That Newly Acquired Bcr-Abl Kinase Domain Mutations Leading to Relapse Are Mainly Detected during the First Year

Contributo in Atti di convegno

Long-lasting memory-restingand memory-effector CD4+ T cells in human X-linked agammaglobulinemia.

Articolo

Long-term follow-up of the Italian trial of interferon- versus conventional chemotherapy in chronic myeloid leukemia

Articolo

Long-term outcome and lineage-specific chimerism in 194 Wiskott-Aldrich Syndrome patients treated by hematopoietic celltransplantation between 1980-2009: an international collaborative study.

Articolo

Long-term outcome following hematopoietic stem cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and the European Group for Blood and Marrow Transplantation

Articolo

Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A

Articolo

Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: achievements and prospects

Articolo

Mature CD10+ and immature CD10- neutrophils present in G-CSF-treated donors display opposite effects on T cells

Articolo

Meta-Analysis on Incidence of Inhibitors in 1,945 Previously Untreated Patients Treated with Recombinant Factor VIII Products: Is There a Difference?

Abstract

Microbial Contamination of Haematopoietic Stem Cell Products: A Single Centre Experience

Articolo

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1.

Articolo

Minimal Residual Disease Detection at RNA and Leukemic Stem Cell (LSC) Level. Comparison of Qpcr, d-PCR and CD26 Stem Cell Measurements in Chronic Myeloid Leukemia (CML) Patients in Deep Molecular Response (DMR)

Abstract

Minimal residual disease monitoring by quantitative Real Time PCR during tratment with STI571 for bcr/abl positive acute lymphoblastic leukemia.

Abstract

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis

Articolo

Missense mutations of the WASP gene cause intermittent X-linked thrombocytopenia

Articolo

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

Articolo

Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes.

Articolo

Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products

Articolo

Molecular Monitoring of NPM1 Is a Useful Tool for Detecting Early-Stage Relapse and to Guide Pre-Emptive Treatment Approaches in Patients with NPM1-Mutated Acute Myeloid Leukemia

Abstract

Molecular profiling reveals immunogenic cues in anaplastic large cell lymphomas with DUSP22 rearrangements

Articolo

Molecular therapy of AML: a new and rapid method to characterize novel genetic variants of Flt3 gene.

Abstract

Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hot spots, effect on transcription and translation and phenotype/genotype correlation.

Articolo

Neutropenia-associated mutations in PRDM5, a novel epigenetic regulator of hematopoiesis.

Abstract

Neutropenia-associated mutations of PFAAP5, a novel protein mediating transcriptional repressor interaction between Gfi1 and neutrophil elastase.

Abstract

New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein.

Articolo

New signaling pathways for hepcidin regulation.

Recensione

Next Generation Sequencing and Microrna Assay in a Cohort of Patients Affected By Myelodysplastic Syndromes. an Analysis of Clinical and Genotypic Features

Articolo

Nomenclature of monocytes and dendritic cells in blood.

Articolo

Nonredundant role of CCRL2 in lung dendritic cell trafficking.

Articolo

Novel markers of normal and neoplastic human plasmacytoid dendritic cells.

Articolo

One Year of Intermittent Imatinib (IM) Treatment (InterIM) Maintains the Complete Cytogenetic Response (CCgR) Previously Achieved with Standard IM Therapy In Elderly (≥ 65 years) Ph+ CML Patients – EudraCT Number 2007-005102-42, ClinicalTrials.Gov NCT 00858806.

Abstract

P2X1 receptor activation in HL60 cells.

Articolo

PAX5 Wild-Type without IKZF1 (Ikaros) Deletion Is Associated with Prolonged Disease-Free Survival and Low Rate of Cumulative Incidence of Relapse in Adult BCR-ABL1-Positive Acute Lymphoblastic Leukemia (ALL): On Behalf of GIMEMA AL Working Party.

Abstract

PI-PLCBETA1 GENE METHYLATION AND EXPRESSION AS A RELIABLE AND DYNAMIC MARKER OF CLINICAL RESPONSE TO 5-AZACYTIDINE IN PATIENTS WITH LOW-RISK MYELODYSPLASTIC SYNDROMES.

Abstract

Parameters of Protein Metabolism and Thyroid Function As Predictors in a Scoring System for Acute and Chronic Graft-Versus-Host Disease

Abstract

Patterns of Lymphocyte Subsets and Index of Bone Marrow Output (KRECs) Correlate Differently with Graft-Versus-Host Disease and Relapse

Abstract

Phase II Multicentric Explorative Study of Intermittent Imatinib (IM) Treatment (INTERIM) in Elderly Patients with Ph+ Chronic Myeloid Leukemia (CML) Who Achieved a Stable Complete Cytogenetic Response (CCgR) with Standard IM Therapy.

Abstract

Phenotype and genotype of interfollicular large B cells, a subpopulation of lymphocytes often with dendritic morphology

Articolo

Post Induction and Post Consolidation Measurable/Minimal Residual Disease Predict Relapse in NPM-1 Positive AML. Outcome of Treatment Relapse. a Single Center Experience

Abstract

Potent in vivo anti-tumor activity of extracellular vesicles isolated from genetically engineered primary mesenchymal stromal cells expressing the trans-membrane TNF-Related Apoptosis-Inducing Ligand (TRAIL)

Contributo in Atti di convegno

Potentiality of Bone Marrow-Derived Mesenchymal Stromal Cells (BM-MSCs) to Differentiate into the Osteogenic Lineage in in Vitro Model of Tissue Regeneration

Abstract

Pre-Emptive Donor Lymphocyte Infusion As Optimal Treatment for Relapsed Acute Myeloid Leukemias and Myelodysplastic Syndromes Following Allogeneic Stem Cell Transplantation: Insights from a French-Italian Study on 134 Patients

Abstract

Preclinical Rationale for the Use of the Combined Treatment with the AKT Inhibitor Perifosine and the Multikinase Inhibitor Sorafenib in Hodgkin Lymphoma

Abstract

Preclinical Rationale for the Use of the Multikinase Inhibitor Sorafenib in the Treatment of Human Lymphomas

Abstract

Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders

Articolo

Prognostic Significance of Immunoglobulin Phenotype in B Cell Chronic Lymphocytic Leukemia.

Articolo

Progression-Free Survival but Not Overall Survival Is Superior in Relapsed/Refractory Large B-Cell Lymphomas Treated with Axicabtagene Ciloleucel Compared to Tisagenlecleucel: Results of the CART-SIE Real Life Italian Study

Abstract

Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.

Articolo

Prolonged imatinib mesylate therapy in patients with chronic phase CML refractory to interferon causes a reduction of the levels of bcr/abl transcript which is independent from the cytogenetic response to treatment.

Abstract

Psychosocial well-being in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) and their caregivers: A prospective study

Abstract

Pulsed ATRA as single therapy restores long term remission in molecular positive acute promyelocytic leukemia: real-time quantitation of minimal residual disease

Abstract

Quantification of BCR/ABL levels by real-time RT-PCR correlates with cytogenetic response in patients with chronic myeloid leukemia (CML).

Abstract

Quantitative RT-PCR identifies a threshold of CBFbeta-MYH11 transcript below which continuous complete remission is likely in inv(16)-positive acute myeloid leukemia.

Abstract

RIC Allogeneic Transplantation Improves the Overall and Progression-Free Survival of Hodgkin Lymphoma Patients Relapsing after Autologous Transplantation: A GITMO Retrospective Study Based on Time of HLA-Typing and Donor Availability.

Abstract

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload.

Articolo

Rapid detection of Flt3-ITD in acute myeloid leukemia patients by DF-HPLC

Abstract

Real time quantification of minimal residual disease in inv(16)-positive acute myeloid leukemia may indicate arisk for clinical relapse and may identify patients in curable state

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Real-world outcomes of total body irradiation-based conditioning in allogeneic hematopoietic stem cell transplantation: A single-center retrospective study

Abstract

Rebalancing Iron Homeostasis and Erythropoiesis through Tfr2 Inhibition for Correction of Anemia in CKD

Abstract

Receptor-type protein tyrosine phosphatase gamma (PTPgamma), a new identifier for myeloid dendritic cells and specialized macrophages.

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Reduced Relapse and Improved Survival in Chemosensitive Hodgkin Lymphoma Patients Undergoing Haploidentical Related Donor Compared to HLA-Identical Donor Transplantation

Abstract

Regulation of dendritic cell migration and adaptive immune response by leukotriene b4 receptors: a role for LTB4 in up-regulation of CCR7 expression and function

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Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease causing from disease modifying TNFRSF13B variants in antibody deficiency syndromes.

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Remission Status at Transplantation and Treatment History Determine the Survival Chances of Patients after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia Who Had Received Pre-Treatment with Idelalisib: A Report from the EBMT Chronic Malignancies Working Party

Abstract

Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome

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Role of Different Hematologic Variables in Defining the Risk of Malignant Transformation in Monoclonal Gammopathy.

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Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma.

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Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies.

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SHP-1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome-positive cells derived from patients with chronic myeloid leukemia.

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SIRPB1 Is a Strong Predictor Biomarker of Response to 5-Azacitidine Therapy in MDS and AML Patients

Abstract

ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: Modulation of intracellular calcium homeostasis

Articolo

SU11657, a FLT3-Targeted Tyrosine Kinase, has Pro-Apoptotic Activity on Leukemia Cells In Vitro.

Abstract

Secondary Myeloid Neoplasms after CD19 CAR-T Cell Therapy: Real-Life Multicenter Data from the Clonhema Study

Abstract

Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis

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Severe impairment of IFN-γ and IFN-α responses in cells of a patient with a novel STAT1 splicing mutation.

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Single Cell Analysis of Circulating Endothelial Cells in Allogeneic Hematopoietic Stem Cell Transplant; To Whom Do They Belong: Host or Donor?

Abstract

Single cell analysis of macrophage chemotactic protein-1 (MCP-1)-regulated cytosolic Ca++ increase in human adherent monocytes

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Sirolimus plus prednisone for Erdheim-Chester disease: An open-label trial

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Specific binding sites for H-ferritin on human lymphocytes: modulation during cellular proliferation and potential implication in cell growth control

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Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited anti-tumor activity

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Splenectomy and risk factor of blastic transformation in myelofibrosis with myeloid metaplasia

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Standardization of Two Dpcr Platforms for Detection of BCR/ABL1 - Minimal Residual Disease (MRD) in Ph+ Chronic Myeloid Leukemia (CML)

Abstract

Stimulated CAR-T cells from non-Hodgkin lymphomas patients engage and activate monocytes via extracellular vesicles

Abstract

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide.

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Structural and functional basis for JAK3-deficient severe combined immunodeficiency.

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Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis

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TARGETING HRASV12G EXPRESSION TO THE ZEBRAFISH EARLY HEMOGENIC PROGENITORS INDUCES A MYELOPROLIFERATIVE DISORDER BY REPRESSING THE NOTCH PATHWAY.

Abstract

Tat-human immunodeficiency virus-1 induces human monocyte chemotaxis by activation of vascular endothelial growth factor receptor-1.

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Tfr2 Genetic Deletion Makes Transfusion-Independent a Murine Model of Transfusion-Dependent β-Thalassemia

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The CXCR4 mutations in WHIM syndrome impair the stability of the T-cell immunologic synapse.

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The EUROclass trial: defining subgroups in common variable immunodeficiency.

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The Effect of Measurable Residual Disease at the Time of Allogeneic Hematopoietic Cell Transplantation on Outcomes in Patients with Acute Myeloid Leukemia: A Meta-Analysis

Abstract

The Risk of Secondary Myelodysplastic Syndrome/Acute Leukemia Following High-Dose Yttrium-90 Ibritumomab Tiuxetan Is Analogous to That Observed Following High-Dose Chemotherapy: a Matched-Pair Analysis In Non-Hodgkin Lymphoma Patients

Abstract

The T-cell receptor repertoires expressed by CD4+ and CD4- large granularlymphocytes derived from the same patients suggest the persistent action of animmune-mediated selection process

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The achievement of molecular complete remission during treatment with imatinib mesylate correlates with relapse free survival and overall survival in patients with bcr/abl positive acute lymphoblastic leukemia.

Abstract

The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage

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The influence of purified recombinant human heavy-subunit and light-subunit ferritins on colony formation in vitro by granulocyte-macrophage and erythroid progenitor cells

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The role of chemerin in the co-localization of NK and dendritic cell subsets into inflamed tissues.

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The toll-like repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells.

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The viral chemokine macrophage inflammatory protein-II is a selective Th2 chemoattractant.

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The yin and yang of Activin A.

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Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2

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Transcriptomic analysis of CD34⁺ cells in myelofibrosis highlights their role in extracellular matrix dysregulation and marrow fibrosis

Abstract

Tumor-associated macrophages as major source of APRIL in gastric MALT lymphoma

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Unraveling the complexity of tyrosine kinase inhibitor-resistant populations by ultra-deep sequencing of the BCR-ABL kinase domain

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Updating Long-Term Outcome of Intermittent Imatinib (INTERIM) Treatment in Elderly Patients with Ph+-CML

Abstract

Urinary Protein Levels in Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma (SMM) Predict Severe Disease Related Complications at Myeloma Progression

Abstract

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations.

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WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function

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WT1 Monitoring of Minimal Residual Disease (MRD) in Patients with Acute Myeloid Leukemia.

Abstract

X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease.

Articolo

• Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.

Articolo

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