RADEGHIERI Annalisa

Education: 2022-present: Associate Professor (permanent) SSD MED/46 Biotechnology and Methods in Laboratory Medicine 2009-2022: Assistant Professor (permanent) SSD BIO/12 – Clinical Biochemistry and Molecular biology, Department of Molecular and Translational Medicine- University of Brescia 2005-2009: Assistant Professor (fixed term) SSD BIO/12 – Clinical Biochemistry and Molecular biology-Department of Biomedical Sciences and Biotechnologies, University of Brescia 2004-2005: Post-doctoral fellowship at Department of Biomedical Sciences and Biotechnologies, University of Brescia 2004: PhD in Applied Biocatalysis and Industrial Microbiology, University of Bologna, Italy 2000: Degree in Industrial Biotechnology, full marks with honour, University of Bologna, Italy. 1999: Summer student at EMBL, European Molecular Biology Laboratory Research and professional experience 2022-present: Associate Professor (permanent) SSD MED/46 Biotechnology and Methods in Laboratory Medicine. She heads the Extracellular vesicles laboratory, together with Paolo Bergese, focusing on the biochemical and biophysical characterization of EV surface interactions with proteins and nanoparticles, towards the development of new diagnostics and new therapeutics. 2009-2022: Assistant Professor (permanent), Department of Molecular and Translational Medicine- University of Brescia. She is member of an interdisciplinary group, headed by Prof. Paolo Bergese, where she supervises the biochemistry and molecular biology unit at the interface with nanotechnologies and biophysics. She is interested in subcellular and extracellular trafficking of proteins and the study of extracellular vesicles in diagnostics and research. 2005-2009: Assistant Professor (fixed term) Department of Biomedical Sciences and Biotechnologies, University of Brescia. Research activity in biochemistry and cell trafficking field (adaptor proteins). 2004-2005: Post-doctoral fellowship at Department of Biomedical Sciences and Biotechnologies, University of Brescia. Research topic: study of the internalization of membrane integrins. 2001- 2003: University of Bologna, Department of Industrial Chemistry: Doctoral fellow in Applied Biocatalysis and Industrial Microbiology. Research topic: Structural and functional studies on procaryotic DNA polymerases. 2002-2003: Marco Polo Fellowship award (University of Bologna) for PhD Host student at The Scripps Research Institute, La Jolla, CA (USA). Research topic: DNA polymerases evolution through phage display technology. 1999-2000: research intnership at the Department of Industrial Chemistry, University of Bologna. Research topic: Directed evolution of enzymes by means of E.coli mutator strains. 1999: Summer student at EMBL, European Molecular Biology Laboratory, Heidelberg (Germany). Research topic: Developmental biology of Xenopus laevis. Scientific track records: ORCID profile: orcid.org/0000-0003-2737-1090 Researcher ID: E-4841-2016 Scopus author ID: 6508039511 She is co-author of 51 articles (47 published, 1 in press, 2 in preparation) and 2 book chapters in international peer-reviewed journals, with 9835 citations and an h-index of 23 on Google Scholar. orcid.org/0000-0003-2737-1090. Grants: Co-PI of the research unit UO2 for the project “Muscle tissue extracellular vesicles: novel biomarkers for sepsis related Intensive Care Unit Acquired Weakness (ICU-AW)” (Italian Ministry of Health – through the program Ricerca Finalizzata). Total amount € 837.347,00; Research Unit amount €147.823,00. Responsible for research activities for the project “Hypermobile Ehlers-Danlos syndrome and Hypermobility spectrum disorders: destructuring the fibroblast secretome to define bioactive molecules and disease mechanisms, and in vivo translational studies”, Ehlers-Danlos Society (NY, NY, US). PI: Prof.Marina Colombi. Amount € 170.000,00. Scientific collaborator in the Coordinat