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PIOVANI GIOVANNA

PIOVANI GIOVANNA

Docenti di ruolo di IIa fascia
Department of Molecular and Translational Medicine
Course Catalogue:
https://unibs.coursecatalogue.cineca.it/docente-ma...

Gruppo 05/BIOS-10 - BIOLOGIA CELLULARE E APPLICATA

Settore BIOS-10/A - Biologia cellulare e applicata
Academic degrees 1981: High School Diploma 1987: Degree in Biological Science,University of Parma 1988: Enabling the profession of biologist and professional certification 1991: Specialization in Human Cytogenetic (Inst. General Biology and Medical Genetics, University of Pavia). 1995: Course qualification for technical quality assurance (UNI EN ISO 9000) at the Faculty of Chemistry, University of Bologna 2003: Winner a competition for a position of Ricercatore Universitario in the Faculty of Medicine of the University of Brescia Academic and Professional training 1984-87 Student visitor at the Institute of Pathology, University of Parma 1987-90 Biologist fellow at the Department of Medical Genetics, 'University of Parma 1989-91 Biologist visitor at the Department of Human Cytogenetics, University of Pavia 1990 Biologist visitor at the Laboratory of Experimental Oncology A of 'National Cancer Institute of Milan-Biologist visitor at the Laboratory of Clinical Cytogenetics Mangiagalli Milan 1990-96 Biologist researcher and Cytogenetics Laboratory Manager; at the Section of Hematology, University of Parma; 1997- 2000 Biologist visitor at the Biology and Genetic Section, University of Brescia 2000-01 Parasubordination contract for research activities (research grant) at Biology and Genetic Section, University of Brescia 2001-05 Employee at the University of Brescia, Biology and Genetics Section as a Technical EP/EP1 2005 at today Researcher disciplinary 05F1 at Biology and Genetic Section at the University of Brescia 2011 Lecturer and tutor in PhD school. Teaching activities Courses of General Biology, Cytogenetics Cell Biology, Cell Culture, DNA Technology, Functional Genomics in Courses for Degrees in medical professionals at the University of Brescia, 2005-2017 Research/professional experience The principal research points, are the following: - cell cultures for genomic and genetic study; - cell culture of mesenchymal cells, amniotic fluid cells -Studies on induced pluripotent cells -chromosome structure; -studies on karyotype/phenotype correlation in constitutional and acquired cytogenetic abnormalities -studies on defining the molecular causes of chromosome rearrangements with molecular cytogenetics(FISH) -studies on the chromosome variability in hematological neoplastic diseases and hemopoietic stem cells -DNA profiling -studies with the SNP-array technology; -studies of gene expression (RT-PCR)
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Curriculum Vitae

Giovanna Piovani, University of Brescia (UNIBS)

Assistant Professor Department of Molecular and Translational Medicine, Adjunct Professor of Applied Biology, University of Brescia, Italy

Education
1987 Degree in Biological Science University of Parma
1988 Enabling the profession of biologist and professional certification
1991 Specialization in Human Cytogenetic, University of Pavia

Professional appointment
University of Parma
1992-96 Scholarship and Cytogenetics Lab Head, Hematology Division
1987-90 Trainee, Department of Medical Genetics
1984-87 Trainee at the Institute of Pathology
University of Pavia
1989-91 Trainee, Department of Human Cytogenetics, University of Pavia
University of Milan
1990-91 Trainee, Laboratory of Experimental Oncology, National Cancer Institute
University of Brescia
2005- Assistant Professor (BIO 13) and Lab Head, Biology and Genetic Division, Department of Molecular and Translational Medicine
2005- Adjunct Professor of Applied Biology (BIO 13)
2000-04 Research fellowship and Molecular Cytogenetic Lab Head, Biology and Genetic Division, Department of Biomedical Sciences and Biotechnologies
1997- 2000 Scholarship, Biology and Genetic Division
2021 National Scientific Qualification as Associate Professor of Applied Biology (2021-2030)
Area of research and expertise
The principal interest is applied cellular biology and chromosomal study to identify gene-disease and genotype-phenotype correlation.
The current interest is the generation of human inducible pluripotent stem cells (iPSC) to study cellular and molecular underpinnings of chromosomal syndrome Cri du Chat, and also of develop-mental and neuropsychiatric disorders such as Mood Disorders, Schizophrenia.
My principal line of research is aimed to study the molecular and functional mechanism of the deleted genes, involved in Cri du chat syndrome, in human neurons derived from iPSC as translational tool for precision medicine and drug discovery in this syndrome.
Another line of research is cellular studies in endothelial and mesenchymal stromal cells aimed to regenerative medicine.
Genotoxicity studies

Grants and Coordination of Scientific Projects (2013-2020)
At UniBS
Partecipant, “Neuroinflammation in major depressive disorder with anxious distress: a precision medicine approach based on human cell biology, imaging, genetics, and biomarkers of inflammation”. Grant from Fondazione Cariplo, Milan. Coordinator professor Francesco Benedetti, University Vita e Salute San Raffaele, Milan (2020-2023)
Partecipant,“ Optimization of 3d printed metal Implants Biocompatibility for faster osseointegration and healing”, Italy-Israel R&D Cooperation Program 2018, Coordinator professor Elisabetta Ceretti, University of Brescia (2018-2021)
Partecipant, “iPS-derived human Cardiomyocytes: a powerful tool to investigate the cellular mechanisms of genetically determined Lone AtRIal Fibrillation (CLARIFY)” Fondazione Cariplo, Milan. Coordinator professor Patrizia Dell’Era, University of Brescia (2016-19)
PI, "Evaluation of possible genetic alterations in cell lines after in vitro amplification" MINISTRY OF HEALTH “Ricerca Corrente 2014” grant (2015-2017)
PI, "Identification of a stabilized cell line for the production of the vaccine for the prevention of infection as an alternative system to primary implantation cell cultures from primate organs” MINISTRY OF HEALTH “Ricerca Corrente 2013” grant (2014)
PI, “Validation of the chromosomal structure of cellular products for advanced therapy” Research agreement with Cell Factory Mayer, Firenze (2014-2016)

Membership of Scientific Societies
Member of Stem Cell Research Italy association (SCRI)(since 2016)
Member of Gruppo Italiano Staminali Mesenchimali – GISM (since 2016)
Member of the European Cytogenetic Association (ECA) (since 2010)
Member of the Italian Society of Applied Biology and Genetic (AIBG) (since 2005).

Referee/Evaluator for peer-reviewed journals/agencies (selection)
Journals
Associate Editor: BMC medical genomics
Reviewer: Frontiers in Neuroscience, Stem cell research, Bio Protocoll, Molecular Cytogenetics, Molecular genetics and genomics
Agencies
Reviewer at MIUR REPRISE
Reviewer of “SIR” projects (2015), of “PRIN projects 2015” also with the role of Rapporteur (2016). Currently reviewer of FISR 2020 projects.

Author of 42 publications (including Stem Cell Research, Scientific reports, Mol Neurobiology, Neural Plasticity, Biochem Biophys Res Commun.)
Total number of citations: 309 (Scopus), 409 (GoogleScholar)
H index: 11 (Scopus), 16 (Google Scholar)

Teaching activities
At UniBS (since 2005)
Applied Biology (BIO13) (CFU: 1.0) Degree Course in Nursing
Principles of biotechnological diagnostics (BIO13) (CFU: 1.0) Degree Course in Biotechnology
Cytogenetics, molecular and medical genetics (BIO13) (CFU: 2.0) Degree Course in Biomedical laboratory techniques
Biomedical Sciences (BIO13) (CFU: 2.0) Degree Course in Biomedical laboratory techniques
Basic Biomedical Sciences (BIO13) (CFU: 3.0) Degree Course in Dental School

Fields (11)


LS2_1 - Genomics, comparative genomics, functional genomics - (2016)

LS2_6 - Molecular genetics, reverse genetics and RNAi - (2016)

LS3_11 - Cell genetics - (2016)

LS3_12 - Stem cell biology - (2016)

LS3_3 - Cell cycle and division - (2016)

LS3_5 - Cell differentiation, physiology and dynamics - (2016)

LS5_2 - Molecular and cellular neuroscience - (2016)

LS6_6 - Immunogenetics - (2016)

LS7_10 - Environment and health risks, occupational medicine - (2016)

LS7_2 - Diagnostic tools (e.g. genetic, imaging) - (2016)

LS7_6 - Gene therapy, cell therapy, regenerative medicine - (2016)

Member of

Cytogenetics and biology of stem cells in chromosomal and tumor pathologies
Group

Collaborates with

Monogenic disorders in vitro modeling
Group

Publications (84)

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Third Mission

Organizzazione di concerti, spettacoli teatrali, rassegne cinematografiche, eventi sportivi, mostre, esposizioni e altri eventi di pubblica utilità aperti alla comunità (Organizzatore) - In nome loro
Department of Civil, Environmental, Architectural, Engineering and Mathematics
Department of Mechanical and Industrial Engineering
Department of Molecular and Translational Medicine
Università degli Studi di Brescia (03/11/2025 - 03/11/2025) 20251103
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