Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy
Academic Article
Publication Date:
2016
Abstract:
Endothelin-1 (ET-1) is an endogenous vasoconstrictor implicated in pulmonary and systemic hypertension, as well as ventricular dysfunction, through effects on vascular smooth muscle, the kidneys, and cardiomyocytes. We aimed to determine the association between serial ET-1 levels and acute heart failure patient outcomes.
CRIS type:
1.1 Articolo in rivista
Keywords:
Acute heart failure; Endothelin-1; Prognosis
List of contributors:
Perez, Antonio L; Grodin, Justin L; Wu, Yuping; Hernandez, Adrian F; Butler, Javed; Metra, Marco; Felker, G Michael; Voors, Adriaan A; Mcmurray, John J; Armstrong, Paul W; Starling, Randall C; O'Connor, Christopher M; Tang, W H Wilson
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