Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data

Cancer; Somatic single nucleotide variants; Whole exome sequencing; Algorithms; Genomics; High-Throughput Nucleotide Sequencing; Humans; Mutation; Neoplasms; Sensitivity and Specificity; Software; Exome; Polymorphism, Single Nucleotide; Structural Biology; Biochemistry; Molecular Biology; Computer Science Applications1707 Computer Vision and Pattern Recognition; Applied Mathematics