Person
RUSSO ISABELLA
Docenti di ruolo di IIa fascia
Course Catalogue:
Biology and pathology of LRRK2 protein in glial cells. Interplay between Glia and Neurons in Parkinson's disease.
Communications
Fields (2)
Free text keywords (4)
ALPHA-SYNUCLEIN
GLIA
LRRK2
PARKINSON'S DISEASE
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Research fields
EXPLORING NEW ROLES OF PARKINSON'S DISEASE KINASE LRRK2 IN GLIAL CELLS
Our research group is interested in studying the molecular mechanisms underlying the early events of neurodegeneration in Parkinson's disease with a particular interest in the dysfunctions of the glia biology. The main goal of this project is to identify new roles of the LRRK2 protein in glial cells and to explore their impact on neuronal functions. Pathological mutations in the LRRK2 gene are the most common cause of familial Parkinson's cases.
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Collaborates with
Other research activities (7)
Clusterin in Parkinson’s Disease: From Biomarker Discovery to Therapeutic Targeting
Progetto PRIN 2026 - PRIN bando 2026
Project
Scientific Manager
Exploring astrocytic-derived Clusterin as a modulator of alpha-synuclein pathology: implications for alpha-synucleinopathies
Bando Fondazioni Private
Project
Scientific Manager
Lo chaperone molecolare Clusterin come bersaglio terapeutico per la malattia di Parkinson
Bando Fondazioni Private
Project
Scientific Manager
Modulation of Clusterin as a novel disease-modifying strategy in a genetic model of Parkinson’s Disease
Bando Fondazioni Private
Project
Scientific Manager
Modulation of the chaperone Clusterin as a novel disease-modifying strategy for Parkinson’s Disease
Bando Fondazioni Private
Project
Scientific Manager
Targeting Clusterin to Slow Parkinson’s Disease Progression
Bando Fondazioni Private
Project
Scientific Manager
The chaperone Clusterin as a novel therapeutic target for Parkinson’s disease
Bandi da altri Organismi Internazionali
Project
Scientific Manager
No Results Found
Publications (76)
Awards and honors (3)
Travel Grant for LRRK2: Ten years along the road to therapeutic intervention Award,
conferred by Biochemical Society - 2016
CARIPLO - Young researcher career grant,
conferred by Fondazione Cariplo - 2016
Travel Grant Award for World Parkinson Congress 2013,
conferred by World Parkinson Coalition - 2013
No Results Found