Lack of correlation between blood lead and serum prolactin levels among lead exposed workers
Articolo
Data di Pubblicazione:
2012
Abstract:
A cross sectional case (241 males occupationally exposed to lead)–control (102 males unexposed to lead) study was
performed with the aim of evaluating the relationship between serum prolactin (S-PRL) and lead blood (PbB) levels.
A meta-analysis of S-PRL levels in similar studies was also carried out. No difference of S-PRL between groups or any
relationship between PbB and S-PRL levels was found. The meta-analysis showed a slight increase of S-PRL levels
among exposed people, the weighted means falling within the reference values of the biomarker. The results do not
support a routine use of S-PRL as a biomarker of effect in lead exposed workers.
performed with the aim of evaluating the relationship between serum prolactin (S-PRL) and lead blood (PbB) levels.
A meta-analysis of S-PRL levels in similar studies was also carried out. No difference of S-PRL between groups or any
relationship between PbB and S-PRL levels was found. The meta-analysis showed a slight increase of S-PRL levels
among exposed people, the weighted means falling within the reference values of the biomarker. The results do not
support a routine use of S-PRL as a biomarker of effect in lead exposed workers.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
prolactin; lead neurotoxicity; occupational Exposure; effect biomarker
Elenco autori:
Catalani, Simona; DE PALMA, Giuseppe; Cesare, Tomasi; Rossella, Alinovi; Antonio, Mutti; Apostoli, Pietro
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