Data di Pubblicazione:
2021
Abstract:
Aggressive pituitary tumours (APTs) are characterised by unusually rapid growth and lack of response to standard treatment. About 1-2% develop metastases being classified as pituitary carcinomas (PCs). For unknown reasons, the corticotroph tumours are overrepresented amongst APTs and PCs. Mutations in the ATRX gene, regulating chromatin remodelling and telomere maintenance, have been implicated in the development of several cancer types, including neuroendocrine tumours.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
ATRX (alpha thalassemia/mental retardation syndrome X-linked); Cushing’s disease; aggressive PitNETs; pituitary adenoma; pituitary carcinoma
Elenco autori:
Casar-Borota, Olivera; Boldt, Henning Bünsow; Engström, Britt Edén; Andersen, Marianne Skovsager; Baussart, Bertrand; Bengtsson, Daniel; Berinder, Katarina; Ekman, Bertil; Feldt-Rasmussen, Ulla; Höybye, Charlotte; Jørgensen, Jens Otto L; Kolnes, Anders Jensen; Korbonits, Márta; Rasmussen, Åse Krogh; Lindsay, John R; Loughrey, Paul Benjamin; Maiter, Dominique; Manojlovic-Gacic, Emilija; Pahnke, Jens; Poliani, Pietro Luigi; Popovic, Vera; Ragnarsson, Oskar; Schalin-Jäntti, Camilla; Scheie, David; Tóth, Miklós; Villa, Chiara; Wirenfeldt, Martin; Kunicki, Jacek; Burman, Pia
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