Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study
Articolo
Data di Pubblicazione:
2019
Abstract:
Guideline-recommended doses of angiotensin-converting-enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs), and β blockers are similar for men and women with heart failure with reduced ejection fraction (HFrEF), even though there are known sex differences in pharmacokinetics of these drugs. We hypothesised that there might be sex differences in the optimal dose of ACE inhibitors or ARBs and β blockers in patients with HFrEF.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Female; Heart Failure; Humans; Male; Prospective Studies; Sex Factors; Stroke Volume
Elenco autori:
Santema, B. T.; Ouwerkerk, W.; Tromp, J.; Sama, I. E.; Ravera, A.; Regitz-Zagrosek, V.; Hillege, H.; Samani, N. J.; Zannad, F.; Dickstein, K.; Lang, C. C.; Cleland, J. G.; Ter Maaten, J. M.; Metra, M.; Anker, S. D.; van der Harst, P.; Ng, L. L.; van der Meer, P.; van Veldhuisen, D. J.; Meyer, S.; Lam, C. S. P.; Richards, A. M.; Lam, C. S. P.; Anand, I.; Hung, C. -L.; Ling, L. H.; Liew, H. B.; Narasimhan, C.; Ngarmukos, T.; Park, S. W.; Reyes, E.; Siswanto, B. B.; Shimizu, W.; Zhang, S.; Voors, A. A.
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