Histopathological changes in bone marrow biopsies from patients with chronic myeloid leukaemia after treatment with recombinant alpha-interferon
Articolo
Data di Pubblicazione:
1997
Abstract:
Recombinant alpha-interferon (r-IFN) is an effective therapy for chronic myeloid leukaemia (CML), inducing haematological and major cytogenetic response in 70% and 30% of patients, respectively. In this study we have evaluated the significance of bone marrow (BM) histology on the subsequent response to r-IFN therapy, as well as the morphological changes induced by r-IFN within BM.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Adolescent; Adult; Biopsy; Bone Marrow; Bone Marrow Examination; Cytogenetics; Female; Humans; Interferon Type I; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Recombinant Proteins
Elenco autori:
Facchetti, F; Tironi, A; Marocolo, D; Capucci, A; Ruggeri, G; Bellotti, D; Rossi, G
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