Phosphodiesterase IV inhibition by piclamilast potentiates the cytodifferentiating action of retinoids in myeloid leukemia cells: Cross-talk between the cAMP and the retinoic acid signaling pathways

3',5'-Cyclic-AMP Phosphodiesterases; Animals; Benzamides; Cell Differentiation; Cell Line, Tumor; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasm Transplantation; Pyridines; Retinoids; Second Messenger Systems; Transcription Factors; Transplantation, Heterologous; Treatment Outcome; Tretinoin; Tumor Cells, Cultured; Biochemistry; Molecular Biology; Cell Biology