Data di Pubblicazione:
2004
Abstract:
Objective: Left superior caval vein (LSVC) is reported in 0.3% to
0.5% of the population at autopsy. LSVC is easily recognised during
fetal scanning but its significance is uncertain. We document the
incidence, associations and outcome of LSVC in 1678 consecutive
fetuses with suspected, or at increased risk of congenital heart
disease (CHD) referred to a fetal medicine unit for echocardiography
between 1997 and 2002.
Methods: Systematic ultrasound examination was made using 5
transverse views (abdominal situs, 4 chamber, both outflow tracts
and 3 vessel), colour flow mapping and pulsed Doppler. Diagnosis
was confirmed by postnatal echocardiography, surgery or autopsy.
Both the odds ratio (OR, 95% confidence intervals) for CHD in the
presence of LSVC and the OR of the defect being coarctation (CoA)
were calculated.
Results: Four of the 1230 normal fetuses (0.3%) had a LSVC
compared with 12/448 (2.7%) fetuses with CHD. Hence the OR for
a cardiac defect if LSVC was detected is 8.43 (2.71, 26.29). Four of
16 fetuses (25%) with LSVC had extracardiac malformations and
three (19%) aneuploidy. LSVC was present in 5 of 10 fetuses (50%)
with CoA. The OR of the CHD being a CoA in fetuses with LSVC
was 61.57 (14.48, 261.74).
Conclusions: Persistent LSVC is not a benign finding in the fetus
and is an indication for detailed echocardiography. It may aid in the
diagnosis of fetal CoA.
0.5% of the population at autopsy. LSVC is easily recognised during
fetal scanning but its significance is uncertain. We document the
incidence, associations and outcome of LSVC in 1678 consecutive
fetuses with suspected, or at increased risk of congenital heart
disease (CHD) referred to a fetal medicine unit for echocardiography
between 1997 and 2002.
Methods: Systematic ultrasound examination was made using 5
transverse views (abdominal situs, 4 chamber, both outflow tracts
and 3 vessel), colour flow mapping and pulsed Doppler. Diagnosis
was confirmed by postnatal echocardiography, surgery or autopsy.
Both the odds ratio (OR, 95% confidence intervals) for CHD in the
presence of LSVC and the OR of the defect being coarctation (CoA)
were calculated.
Results: Four of the 1230 normal fetuses (0.3%) had a LSVC
compared with 12/448 (2.7%) fetuses with CHD. Hence the OR for
a cardiac defect if LSVC was detected is 8.43 (2.71, 26.29). Four of
16 fetuses (25%) with LSVC had extracardiac malformations and
three (19%) aneuploidy. LSVC was present in 5 of 10 fetuses (50%)
with CoA. The OR of the CHD being a CoA in fetuses with LSVC
was 61.57 (14.48, 261.74).
Conclusions: Persistent LSVC is not a benign finding in the fetus
and is an indication for detailed echocardiography. It may aid in the
diagnosis of fetal CoA.
Tipologia CRIS:
4.3 Poster
Elenco autori:
L., Pasquini; Fichera, Anna; T., Tan; S. Y., Ho; H., Gardiner
Link alla scheda completa:
Titolo del libro:
Ultrasound in Obstetrics and Gynecology
Pubblicato in: