A novel patient-oriented numerical procedure for ocular drainage devices

A numerical investigation is presented to study heat and fluid flow inside Anterior Chamber (AC) of subject-specific human eyes, modelled with glaucoma drainage devices. The current threedimensional eye model considers Anterior Chamber (AC), Trabecular Meshwork (TM), Schlemm’s Canal (SC) and Collector Channels (CC), employing the Generalized Porous Medium (GPM) approach for modelling ocular porous tissue and cavities. The Intraocular Pressure (IOP) management inside AC of human eye is analyzed, by comparing the results obtained for four drainage devices implanted in a human eye for glaucoma treatment, i.e. ExPRESS® shunt, iStent® inject, Gold Micro Shunt® (GMS) and Silicon Shunt Device (SSD). The numerical result allows predicting the effects on heat and mass transport phenomena, i.e. Aqueous Humor (AH) drainage and IOP, deriving by the installation of these implants on human eyes of a specific patient.